Endoscopy
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See the full rubric →A prospective clinical trial of eus-shear wave measurement of liver and spleen for hepatic fibrosis.
Clinical takeawayFor EUS patients undergoing the procedure and requiring cirrhosis assessment, perform right-lobe and splenic shear wave stiffness measurement using standard transducer pressure. Splenic measurement is highly accurate for cirrhosis detection (AUC 0.962), outperforming APRI and FIB4. Do not rely on EUS-SWM for intermediate fibrosis staging (F2-F3).
What it foundSplenic shear wave stiffness via EUS identified cirrhosis with AUC 0.962, outperforming APRI and FIB4; hepatic stiffness correlated strongly with histologic fibrosis (left lobe r=0.837-0.872, right lobe r=0.748-0.766).
ContextRefines non-invasive cirrhosis detection for the subset of patients already undergoing EUS, with superior accuracy compared to serology-based APRI and FIB4 scores. No head-to-head comparison with transient elastography, the current standard non-invasive test, so relative positioning unclear.
No standard claimed for this paper
Every paper is compared to the standard governing its question. This one is not: either no standard in the corpus matches it, or the comparison did not hold up on review and was withdrawn rather than published unverified. Both are logged.
Kohli DR … Srikureja W · Gastrointestinal Endoscopy · IF 8.0 · PubMed ↗